About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:93609 Fuccillo M, et al., Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct;131(20):5031-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6693507
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tuj1
Detection system: Secondary antibody
Results
Specimen 2C: embryonic day 10.5 (more )
Note: Double labeled: green - Tubb3; red - Casp3 (assay MGI:6693508).
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 2C Expressed ventrally in pockets of positive cells appearing beneath the developing ventral ganglionic eminences.
Specimen 2D: embryonic day 10.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant. Double labeled: green - Tubb3; red - Casp3 (assay MGI:6693508).
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 2D Ventrally located positive earliest differentiating neurons were completely absent in the mutant.
Specimen 2E: embryonic day 12.5 (more )
Note: Double labeled: green - Tubb3; red - Casp3 (assay MGI:6693508).
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present 2E
Specimen 2F: embryonic day 12.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant. Double labeled: green - Tubb3; red - Casp3 (assay MGI:6693508).
Structure Level Pattern Image Note
TS20: telencephalon Present 2F Reduced expression in ventral regions compared with wild-type controls. The pattern of expression resembled that seen in the wild-type lateral ganglionic eminence rather than that observed in the cortex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/09/2025
MGI 6.24 		The Jackson Laboratory