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Gene Expression Data
Assay Details
Assay
Reference: J:155266 Stevens MV, et al., MEKK3 initiates transforming growth factor beta 2-dependent epithelial-to-mesenchymal transition during endocardial cushion morphogenesis. Circ Res. 2008 Dec 5;103(12):1430-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6693389
Gene symbol: Map3k3
Gene name: mitogen-activated protein kinase kinase kinase 3
Antibody: MEKK3 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1A
TS15: atrioventricular endocardial cushion Present Regionally restricted 1A Expression is in the endocardium lining the atrioventricular canal cushions and is weak in mesenchymal cells within the cushion matrix.
Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1B
TS15: atrioventricular endocardial cushion Present Regionally restricted 1B Expression is in the endocardium lining the atrioventricular canal cushions and is weak in mesenchymal cells within the cushion matrix.
Specimen 1C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1C
TS15: primitive ventricle endocardial lining Trace 1C
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 1D
TS17: atrioventricular endocardial cushion Present Regionally restricted 1D Expression is in the endocardium lining the atrioventricular canal cushions and is weak in mesenchymal cells within the cushion matrix.
Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 1E
TS17: atrioventricular endocardial cushion Present Regionally restricted 1E Expression is in the endocardium lining the atrioventricular canal cushions and is weak in mesenchymal cells within the cushion matrix.
Specimen 1F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 1F
TS17: primitive ventricle endocardial lining Trace 1F
Specimen S1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Present Regionally restricted S1B Expression is in the endocardium.
TS20: cardiac muscle tissue Present S1B
Specimen S1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Present Regionally restricted S1C Expression is in the endocardium.
TS20: cardiac muscle tissue Present
Specimen S1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present Regionally restricted S1D Expression is in the endocardium.
TS21: cardiac muscle tissue Present S1D
Specimen S1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cardiac muscle tissue Present Regionally restricted S1E Expression is in the endocardium.
TS21: atrioventricular endocardial cushion Present S1E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory