About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:102464 Lee NV, et al., Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem. 2005 Oct 14;280(41):34796-804
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6690599
Gene symbol: Adamts1
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 1
Antibody: ADAMTS-1 GP12 antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 4B WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4B Wild-type Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Patchy 4B Wild-type Expression is in the apical epithelial tubules and the basement membrane.
Specimen 4B KO: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Structure Level Pattern Image Note
TS23: metanephros Absent 4B KO
Specimen 4Cb: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Fbln1 (assay MGI:6690592).
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4Cc , 4Cb Expression is in the basement membrane of the developing nephron.
TS23: early nephron Present Patchy 4Cc , 4Cb Expression is in the basement membrane of the developing nephron.
Specimen 4Ce: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Fbln1 (assay MGI:6690592).
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4Cf , 4Ce Expression is in the basement membrane of the developing nephron.
TS23: early nephron Present Patchy 4Cf , 4Ce Expression is in the basement membrane of the developing nephron.
Specimen 4Ch: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Fbln1 (assay MGI:6690592).
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4Ch , 4Ci Expression is in the basement membrane of the developing nephron.
TS23: early nephron Present Patchy 4Ch , 4Ci Expression is in the basement membrane of the developing nephron.
Specimen 7Db: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690601).
Structure Level Pattern Image Note
TS23: basement membrane Present Regionally restricted 7Dc , 7Db Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Regionally restricted 7Dc , 7Db Expression is in the apical epithelial tubules and the basement membrane.
Specimen 7De: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690601).
Structure Level Pattern Image Note
TS23: metanephros Absent 7De , 7Df
Specimen 7Dh: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690602).
Structure Level Pattern Image Note
TS23: basement membrane Present Regionally restricted 7Di , 7Dh Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Regionally restricted 7Di , 7Dh Expression is in the apical epithelial tubules and the basement membrane.
Specimen 7Dk: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690602).
Structure Level Pattern Image Note
TS23: metanephros Absent 7Dl , 7Dk
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory