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Gene Expression Data
Assay Details
Assay
Reference: J:250135 Ding M, et al., Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Front Mol Neurosci. 2017;10:121
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6515787
Gene symbol: Gfap
Gene name: glial fibrillary acidic protein
Antibody: anti-GFAP (clone G-A-5)
Detection system: Cy3
Results
Specimen 4C cerebellum WT: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 4C Cerebellum Merged WT , 4C Cerebellum GFAP WT Expression was detected in astrocytes.

Specimen 4C cerebellum Ankfy1/+: postnatal month 6; Ankfy1Gt(RRE069)Byg/Ankfy1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 4C Cerebellum Merged Ankfy1/+ , 4C Cerebellum GFAP Ankfy1/+ An increased number of astrocytes were seen in the Ankfy1/+ cerebellum.

Specimen 4C substantia nigra WT: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: substantia nigra Present 4C Substantia nigra Merged WT , 4C Substantia nigra GFAP WT Expression was detected in astrocytes.

Specimen 4C substantia nigra Ankfy1/+: postnatal month 6; Ankfy1Gt(RRE069)Byg/Ankfy1+ (more )
Structure Level Pattern Image Note
TS28: substantia nigra Present 4C Substantia nigra GFAP Ankfy1/+ , 4C Substantia nigra Merged Ankfy1/+ An increased number of astrocytes were seen in the Ankfy1/+ substantia nigra.

Specimen 4C vestibular nuclei WT: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: vestibular nucleus Present 4C Vestibular nuclei Merged WT , 4C Vestibular nuclei GFAP WT Expression was detected in astrocytes.

Specimen 4C vestibular nuclei Ankfy1/+: postnatal month 6; Ankfy1Gt(RRE069)Byg/Ankfy1+ (more )
Structure Level Pattern Image Note
TS28: vestibular nucleus Present 4C Vestibular nuclei GFAP Ankfy1/+ , 4C Vestibular nuclei Merged Ankfy1/+ An increased number of astrocytes were seen in the Ankfy1/+ vestibular nuclei.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory