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Gene Expression Data
Assay Details
Assay
Reference: J:239610 Taniguchi K, et al., Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning. Eur J Hum Genet. 2017 Feb;25(2):208-215
Assay type: RNA in situ
MGI Accession ID: MGI:6513204
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Probe: Gli3 probe24
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1a control: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: prosencephalon Present 1a control
Specimen 1a cdKO: embryonic day 9.0; Tgif1tm1Caw/Tgif1tm1Caw, Tgif2tm1Dwot/Tgif2tm1Dwot, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: prosencephalon Strong 1a cdKO There is an increase in dorsal expression in this mutant compared to control embryos.
Specimen 1a Nodal+/z;cdKO: embryonic day 9.0; Nodaltm1Rob/Nodal+, Tgif1tm1Caw/Tgif1tm1Caw, Tgif2tm1Dwot/Tgif2tm1Dwot, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: prosencephalon Strong 1a Nodal+/z;cdKO There is an increase in dorsal expression in this mutant compared to control embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory