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Gene Expression Data
Assay Details
Assay
Reference: J:161880 Bergman JE, et al., Study of smell and reproductive organs in a mouse model for CHARGE syndrome. Eur J Hum Genet. 2010 Feb;18(2):171-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6512844
Gene symbol: Gnrh1
Gene name: gonadotropin releasing hormone 1
Antibody: anti-GnRH1 (MAB5456)
Detection system: Secondary antibody coupled to biotin
Results
Specimen 5a: postnatal adult (more )
Structure Level Pattern Image Note
TS28: diencephalon Present Regionally restricted 5a Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
TS28: median eminence Present 5a

Specimen 5b: postnatal adult; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS28: diencephalon Present Regionally restricted 5b Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
TS28: median eminence Present

Specimen 5c: postnatal adult (more )
Structure Level Pattern Image Note
TS28: diencephalon Present Regionally restricted 5c Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
TS28: median eminence Present 5c

Specimen 5d: postnatal adult; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS28: diencephalon Present Regionally restricted 5d Expression is in the organum vasculosum of the lamina terminalis with fibers extending to the median eminence.
TS28: median eminence Present 5d

Specimen 5e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: median eminence Present 5e

Specimen 5f: postnatal adult; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS28: median eminence Present 5f

Specimen 5g: postnatal adult (more )
Structure Level Pattern Image Note
TS28: median eminence Present 5g

Specimen 5h: postnatal adult; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS28: median eminence Present 5h The expression in this heterozygote is reduced compared to wild-type.

Specimen S1a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nose Present Regionally restricted S1a Expression is in migrating neurons alongside the nasal septum.

Specimen S1b: embryonic day 16.5; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS24: nose Present Regionally restricted S1b Expression in this heterozygote is the same as in wild-type.

Specimen S1c: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb Present S1c

Specimen S1d: embryonic day 16.5; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb Present S1d Expression in this heterozygote is the same as in wild-type.

Specimen S1e: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Present S1e

Specimen S1f: embryonic day 16.5; Chd7Whi/Chd7+ (more )
Structure Level Pattern Image Note
TS24: hypothalamus Present S1f Expression in this heterozygote is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory