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Gene Expression Data
Assay Details
Assay
Reference: J:86665 Laurikkala J, et al., Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev Biol. 2003 Dec 1;264(1):91-105
Assay type: RNA in situ
MGI Accession ID: MGI:6512426
Gene symbol: Sostdc1
Gene name: sclerostin domain containing 1
Probe: ectodin cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: skin Strong 6A
TS21: vibrissa Strong 6A
TS21: dorsal root ganglion Present 6A
TS21: ganglion Present 6A Expressed in dorsal root and other ganglia.
Specimen 6B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: skin Strong 6B
TS22: molar Strong Regionally restricted 6B Expressed in the tooth germ except in its center, which was dominated by a strikingly negative round area.
Specimen 7A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: buccal pouch Strong 7A Expressed in the buccal mesenchyme.
Specimen 7B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present 7B
TS21: tooth mesenchyme Present 7B
TS21: enamel knot Absent 7B
Specimen 7C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: tooth Strong Regionally restricted 7C Expressed in the peripheral parts, whereas the enamel knot as well as the epithelium and mesenchyme surrounding it were completely negative.
TS22: enamel knot Absent 7C
Specimen 7D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: inner enamel epithelium Strong 7D
TS24: outer enamel epithelium Strong 7D
TS24: tooth mesenchyme Strong 7D follicle mesenchyme
Specimen 7E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cervical loop Strong 7E
TS27: dental sac Strong 7E
Specimen 7F: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cervical loop Strong 7F
TS27: dental sac Strong 7F
Specimen 7G: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: skin Present 7G
Specimen 7H: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: epidermis Present Regionally restricted 7H Expressed in the epithelial cell layer, except in the basal cells of the newly forming hair placode.
Specimen 7I: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: vibrissa inner root sheath Present 7I
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: collecting duct Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory