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Gene Expression Data
Assay Details
Assay
Reference: J:175386 Maier H, et al., Normal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glands. J Biol Chem. 2011 Jul 22;286(29):25922-34
Assay type: RNA in situ
MGI Accession ID: MGI:6512401
Gene symbol: Cers4
Gene name: ceramide synthase 4
Probe: Cers4 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5E +/+: postnatal (more )
Structure Level Pattern Image Note
TS28: sebaceous gland Present 5E +/+ Specific expression in sebaceous glands.
TS28: back skin Present Regionally restricted 5E +/+ Expression undetectable in keratinocytes.
Specimen 5E -/-: postnatal; Fa2htm1Meck/Fa2htm1Meck (more )
Structure Level Pattern Image Note
TS28: sebaceous gland Strong 5E -/- Expression strongly increased in mutant, apparently due to sebaceous gland enlargement.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory