Klf4 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:165929 Yoshida T, et al., Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation. J Biol Chem. 2010 Jul 2;285(27):21175-84
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6511820
Gene symbol:	Klf4
Gene name:	Kruppel-like transcription factor 4 (gut)

Antibody:	anti-Klf4
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

2A ©

S1A ©

Specimen 2A/S1A: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: heart	Absent		2A , S1A

2B ©

S1B ©

Specimen 2B/S1B: embryonic day 11.5 (more

)

Structure	Level	Image
TS19: heart	Absent	S1B , 2B
TS19: 3rd arch artery	Absent	2B
TS19: 4th arch artery	Absent	2B
TS19: 6th arch artery	Absent	2B
TS19: dorsal aorta	Absent	2B

2C ©

S1C ©

Specimen 2C/S1C: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: heart	Absent		S1C , 2C

2D ©

S1D ©

Specimen 2D/S1D: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: heart	Present		S1D , 2D

2E ©

S1E ©

Specimen 2E/S1E: postnatal day 1 (more

)

Structure	Level	Pattern	Image	Note
TS27: heart	Present		S1E , 2E

2F ©

Specimen 2F: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: heart	Present		2F

2H ©

Specimen 2H: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: aorta smooth muscle	Absent		2H

2I ©

Specimen 2I: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: skeletal muscle	Absent		2I

2J ©

Specimen 2J: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: stomach epithelium	Present		2J
TS28: stomach smooth muscle	Absent		2J

2K ©

Specimen 2K: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: detrusor muscle of bladder	Absent		2K

3C Skin left lower ©

3C Skin left upper ©

Specimen 3C Skin cont: postnatal day 28; Klf4^tm1Khk/Klf4^tm1Khk (more

)

Structure	Level	Pattern	Image	Note
TS28: epidermis	Present		3C Skin left lower , 3C Skin left upper

3C Skin right lower ©

3C Skin right upper ©

Specimen 3C Skin cKO: postnatal day 28; Klf4^tm1Khk/Klf4^tm1Khk, Tagln^tm2(cre)Yec/Tagln⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: epidermis	Present		3C Skin right lower , 3C Skin right upper	Same as in the control.

Specimen 3C Colon cont: postnatal day 28; Klf4^tm1Khk/Klf4^tm1Khk (more

)

Structure	Level	Pattern	Image	Note
TS28: colon epithelium	Present		3C Colon left lower , 3C Colon left upper

Specimen 3C Colon cKO: postnatal day 28; Klf4^tm1Khk/Klf4^tm1Khk, Tagln^tm2(cre)Yec/Tagln⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: colon epithelium	Present		3C Colon right lower , 3C Colon right upper	Same as in the control.

Specimen 3C Heart cont: postnatal day 28; Klf4^tm1Khk/Klf4^tm1Khk (more

)

Structure	Level	Pattern	Image	Note
TS28: heart	Present		3C Heart left upper , 3C Heart left lower

Specimen 3C Heart cKO: postnatal day 28; Klf4^tm1Khk/Klf4^tm1Khk, Tagln^tm2(cre)Yec/Tagln⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: heart	Present		3C Heart right lower , 3C Heart right upper	Reduced expression compared with the control.

Specimen not shown: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: aorta endothelium	Present
TS28: aorta tunica adventitia	Present			Expressed in some cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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