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Gene Expression Data
Assay Details
Assay
Reference: J:157050 Bojanic DD, et al., Differential expression and function of ABCG1 and ABCG4 during development and aging. J Lipid Res. 2010 Jan;51(1):169-81
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6509682
Gene symbol: Abcg1
Gene name: ATP binding cassette subfamily G member 1
Reporter: lacZ
Direct Detection
Results
Specimen 1Ad: embryonic day 10.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS17: nasal pit Present 1Ad
TS17: liver Absent 1Ad

Specimen 1Ae: embryonic day 12.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS20: central nervous system Very strong 1Ae
TS20: eye Very strong 1Ae
TS20: liver Weak 1Ae

Specimen 1Af: embryonic day 15.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS23: embryo Strong Ubiquitous 1Af
TS23: eye Very strong 1Af
TS23: vibrissa Very strong 1Af

Specimen 1Bd: embryonic day 15.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS23: liver Strong Regionally restricted 1Bd Expression is in Kupffer cells and endothelial cells.
TS23: blood vessel endothelium Strong Regionally restricted 1Bd Expression is in endothelial cells in the liver.

Specimen 1Be: postnatal day 0; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS27: liver Strong Regionally restricted 1Be Expression is in Kupffer cells and endothelial cells.
TS27: blood vessel endothelium Strong Regionally restricted 1Be Expression is in endothelial cells in the liver.

Specimen 1Bf: postnatal adult; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS28: liver Strong Regionally restricted 1Bf Expression is in Kupffer cells and endothelial cells.
TS28: blood vessel endothelium Strong Regionally restricted 1Bf Expression is in endothelial cells in the liver.

Specimen 2c: postnatal day 0; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS27: small intestine lamina propria Strong Regionally restricted 2c Expression is in the macrophages of the lamina propria.
TS27: ileum epithelium Absent 2c

Specimen 2d: postnatal adult; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS28: small intestine lamina propria Strong Regionally restricted 2d Expression is in the macrophages of the lamina propria.
TS28: ileum epithelium Absent 2d

Specimen 3c: embryonic day 15.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS23: choroid plexus Present 3c

Specimen 3d: embryonic day 15.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present 3d
TS23: spinal cord Present 3d
TS23: spinal cord ventral horn Present Regionally restricted 3d Expression is in motor neurons.

Specimen 4d: embryonic day 15.5; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS23: retina layer Present Regionally restricted 4Ad Expression is in the ganglion cell layer.

Specimen 4e: postnatal adult; Abcg1tm1Dgen/Abcg1tm1Dgen (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Very strong 4Ae
TS28: retina inner nuclear layer Very strong 4Ae
TS28: pigmented retinal epithelium Absent 4Ae

Specimen not shown +/-: postnatal adult; Abcg1tm1Dgen/Abcg1+ (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Very strong
TS28: retina inner nuclear layer Very strong
TS28: pigmented retinal epithelium Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory