Gene Expression Data
Assay Details
Assay
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Reference:
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J:267460
Hrycaj SM, et al., Hox5 genes direct elastin network formation during alveologenesis by regulating myofibroblast adhesion. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10605-E10614
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6505974
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Gene symbol:
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Eln
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Gene name:
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elastin
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Results
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Specimen
6A:
embryonic day 16.5
(more )
Specimen
6A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS24: lung |
Present |
Regionally restricted |
6A
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Expression exclusively around proximal airway through E16.5.
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TS24: alveolar system |
Absent |
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6A
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No expression in distal airways.
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Specimen
6B:
embryonic day 17.5
(more )
Specimen
6B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
6C:
embryonic day 18.5
(more )
Specimen
6C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS26: alveolar system |
Present |
Regionally restricted |
6C
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Elastin network continues to be elaborated over the nest several days. Authors report a complex elastin network in distal lung by E18.5.
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Specimen
6D:
postnatal day 0
(more )
Specimen
6D:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS27: alveolar system |
Present |
Regionally restricted |
6D
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Elastin network continues post-birth, remodeled into more tightly organized elastin bundles located around alveolar openings.
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Specimen
6E:
postnatal day 3
(more )
Specimen
6E:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 3
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS27: alveolar system |
Present |
Regionally restricted |
6E
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Elastin network continues post-birth, remodeled into more tightly organized elastin bundles located around alveolar openings.
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Specimen
6F:
postnatal day 7
(more )
Specimen
6F:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS28: alveolar system |
Present |
Regionally restricted |
6F
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Elastin network is significantly remodeled with fewer thinner fibers and more tightly organized elastin bundles around alveolar openings.
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