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Gene Expression Data
Assay Details
Assay
Reference: J:36690 Buck CA, et al., Expression patterns of adhesion receptors in the developing mouse lung: functional implications. Cell Adhes Commun. 1996 Aug;4(2):69-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6504915
Gene symbol: Itga6
Gene name: integrin alpha 6
Antibody: anti-alpha6 integrin (GoH3)
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Embryos were staged according to Kaufman, M.H. (1992) The Atlas of Mouse Development. Academic Press, London.
Results
Specimen 3B: embryonic day 10.0 (more )
Note: Double labeled: green - Itga6; red - laminin.
Structure Level Pattern Image Note
TS16: lung mesenchyme Present Regionally restricted 3B Expression is in the extracellular matrix in endothelial cells in the mesenchyme.
TS16: lung vascular element Present Regionally restricted 3B Expression is in the extracellular matrix in endothelial cells in the mesenchyme.
TS16: bronchus epithelium Present Regionally restricted 3B Expression is in the extracellular matrix.
Specimen 3D: embryonic day 12.5 (more )
Note: Double labeled: green - Itga6; red - laminin.
Structure Level Pattern Image Note
TS20: lung mesenchyme Present Regionally restricted 3D Expression is in the extracellular matrix in the mesenchyme.
TS20: lung vascular element Present Regionally restricted 3D Expression is in the extracellular matrix in endothelial cells.
TS20: bronchus epithelium Present Regionally restricted 3D Expression is in the extracellular matrix.
TS20: basement membrane Present 3D
Specimen 3F: postnatal day 0 (more )
Note: Double labeled: green - Itga6; red - laminin.
Structure Level Pattern Image Note
TS27: alveolus epithelium Present Regionally restricted 3F
TS27: basement membrane of epithelium Present Regionally restricted 3F
TS27: bronchiole epithelium Present Regionally restricted 3F
TS27: blood vessel endothelium Weak Regionally restricted 3F Expression is in the arterial endothelium in smaller vessels and capillaries.
TS27: lung vascular element Weak Regionally restricted 3F Expression is in the arterial endothelium in smaller vessels and capillaries.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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