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Gene Expression Data
Assay Details
Assay
Reference: J:105983 Ohyama T, et al., Wnt signals mediate a fate decision between otic placode and epidermis. Development. 2006 Mar;133(5):865-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6504267
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3C Control: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: otic placode Present 3C Control

Specimen 3C CKO: embryonic day 8.75; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode Weak 3C CKO

Specimen 4A Control E8.75: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: otic placode Present 4A 2-1

Specimen 4A CKO-1 E8.75: embryonic day 8.75; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode Weak 4A 2-2

Specimen 4A CKO-2 E8.75: embryonic day 8.75; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode Weak 4A 2-3

Specimen 4A CKO-3 E8.75: embryonic day 8.75; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode Weak 4A 2-4

Specimen 4A Control E9.0: embryonic day 9.0; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode epithelium Present 4A 4-1

Specimen 4A CKO-1 E9.0: embryonic day 9.0; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode Strong Regionally restricted 4A 4-2 Expressed as a mixture of epithelial cells strongly expressing protein and some expressing no protein at all.

Specimen 4A CKO-2 E9.0: embryonic day 9.0; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode epithelium Strong Regionally restricted 4A 4-3 Expressed as a mixture of epithelial cells strongly expressing protein and some expressing no protein at all.

Specimen 4A CKO-3 E9.0: embryonic day 9.0; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: otic placode epithelium Strong Regionally restricted 4A 4-4 Expressed as a mixture of epithelial cells strongly expressing protein and some expressing no protein at all.

Specimen 4B upper: embryonic day 10.5; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 4B2 The residual otocyst consisted of a series of small cysts fused to one another, which tended to consist entirely of either positive or negative cells.

Specimen 4B lower: embryonic day 10.5; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 4B4 The residual otocyst consisted of a series of small cysts fused to one another, which tended to consist entirely of either positive or negative cells.

Specimen 4C CKO: embryonic day 10.5; Ctnnb1tm2.1Kem/Ctnnb1tm2Kem, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 4C CKO beta-cat , 4C CKO Merge The residual otocyst consisted of a series of small cysts fused to one another, which tended to consist entirely of either positive or negative cells.

Specimen 5B Control E8.75: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: otic placode epithelium Present 5B Control left

Specimen 5B Control E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst epithelium Present 5B Control right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory