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Gene Expression Data
Assay Details
Assay
Reference: J:70696 Gowan K, et al., Crossinhibitory activities of ngn1 and math1 allow specification of distinct dorsal interneurons. Neuron. 2001 Aug;31(2):219-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6502610
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Antibody: 4F2
Detection system: Secondary antibody
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 5F: embryonic day 11.5 (more )
Note: Double labeled: green - Lhx1 and Lhx5; red - Pou4f1 (assay MGI:6502611).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present 5F There were Pou4f1+, Lhx1/5+ and Pou4f1+Lhx1/5+ cell populations.
Specimen 5G: embryonic day 11.5; Neurog1tm1And/Neurog1tm1And (more )
Note: Double labeled: green - Lhx1 and Lhx5; red - Pou4f1 (assay MGI:6502611).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present 5G There were Pou4f1+, Lhx1/5+ and Pou4f1+Lhx1/5+ cell populations. Decreased coexpressing cells compared with wild-type.
Specimen 5H: embryonic day 11.5; Atoh1tm1Hzo/Atoh1tm1Hzo (more )
Note: Double labeled: green - Lhx1 and Lhx5; red - Pou4f1 (assay MGI:6502611).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present 5H Pou4f1+ cells were replaced with cells coexpressing Pou4f1 and Lhx1/5.
Specimen 5I: embryonic day 11.5; Atoh1tm1Hzo/Atoh1tm1Hzo, Neurog1tm1And/Neurog1tm1And (more )
Note: Double labeled: green - Lhx1 and Lhx5; red - Pou4f1 (assay MGI:6502611).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present 5I Pou4f1+ cells were replaced with cells coexpressing Pou4f1 and Lhx1/5.
Specimen 5J: embryonic day 11.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Double labeled: green - Lhx1 and Lhx5; red - Pou4f1 (assay MGI:6502611).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present 5J There were no cells coexpressing Pou4f1 and Lhx1/5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory