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Gene Expression Data
Assay Details
Assay
Reference: J:159519 Saharinen P, et al., Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6501774
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Results
Specimen 3D SMA: postnatal adult; Tmem204tm1.1Ali/Tmem204tm1.1Ali (more )
Structure Level Pattern Image Note
TS28: ear Present Regionally restricted 3D SMA Expression in perivascular smooth muscle cells covering dilated lymphatic vessels.
TS28: smooth muscle tissue Present Regionally restricted 3D SMA Expression in perivascular smooth muscle cells covering dilated lymphatic vessels.
Specimen 3E SMA: postnatal adult; Tmem204tm1.1Ali/Tmem204+ (more )
Structure Level Pattern Image Note
TS28: ear Present Regionally restricted 3E SMA Expression in perivascular smooth muscle cells covering lymphatic vessels.
TS28: smooth muscle tissue Present Regionally restricted 3E SMA Expression in perivascular smooth muscle cells covering lymphatic vessels.
Specimen S6A: postnatal adult; Tmem204tm1.1Ali/Tmem204tm1.1Ali (more )
Note: Triple labeled: red - alpha smooth muscle actin (Acta2); green - Vegfr2 (Kdr assay MGI:6501773); white - Lyve1 (assay MGI:6501770).
Structure Level Pattern Image Note
TS28: ear Strong Regionally restricted S6A SMA , S6A merge Increased number of smooth muscle cells associated with lymphatic vessels.
TS28: smooth muscle tissue Strong Regionally restricted S6A SMA , S6A merge Increased number of smooth muscle cells associated with lymphatic vessels.
Specimen S6B: postnatal adult; Tmem204tm1.1Ali/Tmem204+ (more )
Note: Triple labeled: red - alpha smooth muscle actin (Acta2); green - Vegfr2 (Kdr assay MGI:6501773); white - Lyve1 (assay MGI:6501770).
Structure Level Pattern Image Note
TS28: ear Weak Regionally restricted S6B SMA , S6B merge Lymphatic vessels gradually lose the smooth muscle covering.
TS28: smooth muscle tissue Weak Regionally restricted S6B SMA , S6B merge Lymphatic vessels gradually lose the smooth muscle covering.
Specimen S6C SMA: postnatal adult; Tmem204tm1.1Ali/Tmem204tm1.1Ali (more )
Structure Level Pattern Image Note
TS28: ear Strong Regionally restricted S6C SMA Increased number of smooth muscle cells associated with lymphatic vessels.
TS28: smooth muscle tissue Strong Regionally restricted S6C SMA Increased number of smooth muscle cells associated with lymphatic vessels.
Specimen S6D SMA: postnatal adult; Tmem204tm1.1Ali/Tmem204+ (more )
Structure Level Pattern Image Note
TS28: ear Weak Regionally restricted S6D SMA Lymphatic vessels gradually lose the smooth muscle covering.
TS28: smooth muscle tissue Weak Regionally restricted S6D SMA Lymphatic vessels gradually lose the smooth muscle covering.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory