Gene Expression Data
Assay Details
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Assay
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Reference:
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J:163986
Bush JO, et al., Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev. 2010 Sep 15;24(18):2068-80
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6501123
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Gene symbol:
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Shh
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Gene name:
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sonic hedgehog
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Probe:
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Shh probe192
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
S1P:
embryonic day 14.5
(more  )
Note: Genotype indicated as ephrin-B1+/Y
Specimen
S1P:
(close  )
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Genetic Background:
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involves: 129S4/SvJaeSor
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Age:
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embryonic day 14.5
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Sex:
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Male
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Genotype indicated as ephrin-B1+/Y
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: palatal shelf |
Present |
Regionally restricted |
S1P
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Expression in epithelial thickenings (rugae).
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Specimen
S1Q:
(close )
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Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Efnb1tm1.1Sor/Efnb1+
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Age:
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embryonic day 14.5
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Sex:
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Female
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: palatal shelf |
Present |
Regionally restricted |
S1Q
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Authors report rugae patterning is disrupted.
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Specimen
S1R:
(close )
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Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Efnb1tm1.1Sor/Efnb1tm1.1Sor
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Age:
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embryonic day 14.5
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Sex:
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Female
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: palatal shelf |
Present |
Regionally restricted |
S1R
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Authors report a less severe effect.
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Analysis Tools
