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Gene Expression Data
Assay Details
Assay
Reference: J:125316 Reggiani L, et al., The prepattern transcription factor Irx3 directs nephron segment identity. Genes Dev. 2007 Sep 15;21(18):2358-70
Assay type: RNA in situ
MGI Accession ID: MGI:6491979
Gene symbol: Irx3
Gene name: Iroquois related homeobox 3
Probe: IMAGE clone 5056394
Probe preparation: labelled with digoxigenin
Results
Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: early nephron Present 3C Expression in newly forming nephrons in cortex.
TS26: anlage of loop of Henle of cortical renal tubule Present Regionally restricted 3C Expression in developing intermediate tubule epithelia.
Specimen 3G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: comma-shaped body Weak 3G Low level of expression in early comma-shaped bodies.
TS26: medial segment of s-shaped body Weak Regionally restricted 3G Low level of expression confined to intermediate regions of S-shaped bodies.
Specimen 4C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: proximal straight tubule, cortical portion Present Regionally restricted 4C Expression confined to S3 segment of proximal tubule.
Specimen 4F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: proximal straight tubule, cortical portion Present Regionally restricted 4F Expression confined to S3 segment of proximal tubule.
TS28: loop of Henle thin limb Absent 4F No expression in thin limb of Henle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory