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Gene Expression Data
Assay Details
Assay
Reference: J:73417 Mudgett JS, et al., Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10454-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6489536
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 4q: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic blood vessel Present 4q
TS15: chorionic plate Present Regionally restricted 4q Expression is in the endothelium.
TS15: labyrinthine zone Present Regionally restricted 4q Expression is in the endothelium.

Specimen 4r: embryonic day 9.5; Mapk14tm1Mms/Mapk14tm1Mms (more )
Structure Level Pattern Image Note
TS15: extraembryonic blood vessel Present 4r Expression in this mutant is the same as in wild-type.
TS15: chorionic plate Present Regionally restricted 4r Expression in this mutant is the same as in wild-type.
TS15: labyrinthine zone Present Regionally restricted 4r Expression in this mutant is the same as in wild-type.

Specimen 4s: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: extraembryonic blood vessel Present Regionally restricted 4s Expression is in endothelial cells.
TS17: chorionic plate Present Regionally restricted 4s Expression is in endothelial cells.
TS17: labyrinthine zone Present Regionally restricted 4s Expression is in endothelial cells.

Specimen 4t: embryonic day 10.5; Mapk14tm1Mms/Mapk14tm1Mms (more )
Structure Level Pattern Image Note
TS17: extraembryonic blood vessel Present Regionally restricted 4t Expression is in endothelial cells and is the same as in wild-type in the chorionic plate but greatly reduced in the labyrinth layer.
TS17: chorionic plate Present Regionally restricted 4t Expression in endothelial cells of the chorionic plate is the same as in wild-type.
TS17: labyrinthine zone Weak Regionally restricted 4t Expression is in endothelial cells in the reduced labyrinth layer.

Specimen 5a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain blood vessel Present 5a

Specimen 5b: embryonic day 10.5; Mapk14tm1Mms/Mapk14tm1Mms (more )
Structure Level Pattern Image Note
TS17: brain blood vessel Present 5b The pattern of expression varies from wild-type due to the disorganized pattern of the vasculature of the mutant embryo.

Specimen 5c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present 5c

Specimen 5d: embryonic day 10.5; Mapk14tm1Mms/Mapk14tm1Mms (more )
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present 5d The pattern of expression in this mutant varies from wild-type and lacked major blood vessels and instead retained a primitive capillary plexus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory