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Gene Expression Data
Assay Details
Assay
Reference: J:289438 Kischel A, et al., Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6488160
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Results
Specimen 2A Control: embryonic day 16.5 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS24: cortical plate Present 2A Control
Specimen 2A efnb2lox/lox;NesCre: embryonic day 16.5; Efnb2tm2Sor/Efnb2tm2Sor (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS24: cortical plate Weak Regionally restricted 2A efnb2lox/lox;NesCre Significant decrease in number of neurons.
Specimen 2G Control: embryonic day 16.5 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS24: cortical plate Present 2G Control
Specimen 2G efnb2lox/lox;NexCre: embryonic day 16.5; Efnb2tm4Kln/Efnb2tm4Kln, Neurod6tm1(cre)Kan/Neurod6+ (more )
Note: Conditional mutant. Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS24: cortical plate Present 2G efnb2lox/lox;NexCre No apparent difference in number of neurons
Specimen 3A E13.5 Control: embryonic day 13.5 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS21: cortical plate Present 3A E13.5 Control
Specimen 3A E13.5 efnb2lox/lox;NesCre: embryonic day 13.5; Efnb2tm2Sor/Efnb2tm2Sor (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS21: cortical plate Present 3A E13.5 efnb2lox/lox;NesCre
Specimen S4A Control: embryonic day 13.5 (more )
Note: Triple labeled: red - Tbr1; green - Tbr2 (Eomes assay MGI:6488161); black - Draq5.
Structure Level Pattern Image Note
TS21: neocortex Present S4A Control
Specimen S4A efnb2lox/lox;NesCre: embryonic day 13.5; Efnb2tm2Sor/Efnb2tm2Sor (more )
Note: Triple labeled: red - Tbr1; green - Tbr2 (Eomes assay MGI:6488161); black - Draq5.
Structure Level Pattern Image Note
TS21: neocortex Present S4A efnb2lox/lox/NesCre
Specimen 3A E14.5 Control: embryonic day 14.5 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS22: cortical plate Present 3A E14.5 Control
Specimen 3A E14.5 efnb2lox/lox;NesCre: embryonic day 14.5; Efnb2tm2Sor/Efnb2tm2Sor (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS22: cortical plate Present 3A E14.5 efnb2lox/lox;NesCre No statistical difference in number of neurons.
Specimen 3A E18.5 Control: embryonic day 18.5 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS26: cortical plate Present 3A E18.5 Control
Specimen 3A E18.5 efnb2lox/lox;NesCre: embryonic day 18.5; Efnb2tm2Sor/Efnb2tm2Sor (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS26: cortical plate Present 3A E18.5 efnb2lox/lox;NesCre Decrease in neurons is no longer statistically signficant.
Specimen 3A P4 Control: postnatal day 4 (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS28: neocortex Present 3A P4 Control
Specimen 3A P4 efnb2lox/lox;NesCre: postnatal day 4; Efnb2tm2Sor/Efnb2tm2Sor (more )
Note: Double labeled: red - Tbr1; green - Satb2 (assay MGI:6488159).
Structure Level Pattern Image Note
TS28: neocortex Present 3A P4 efnb2lox/lox;NesCre No detectable difference in number of neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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