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Gene Expression Data
Assay Details
Assay
Reference: J:91011 Kurokawa D, et al., Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development. 2004 Jul;131(14):3319-31
Assay type: RNA in situ
MGI Accession ID: MGI:6479850
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA13
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3Ce: embryonic day 10.5 (more )
Note: wild type
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 3Ce
Specimen 3Cf: embryonic day 10.5; Otx2tm2.1Imat/Otx2tm5Sia (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 3Cf In this mutant expression in the isthmus is shifted rostrally and expanded.
Specimen 6Cc: embryonic day 10.5; Otx2tm2.1Imat/Otx2tm6Sia (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 6Cc In this mutant expression in the isthmus there is only a mild shift rostrally and only a mild expansion in expression.
Specimen 7Bc: embryonic day 10.5; Otx1tm1Sia/Otx1tm1Sia, Otx2tm5Sia/Otx2tm5Sia (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Absent 7Bc The isthmus is lost in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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