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Gene Expression Data
Assay Details
Assay
Reference: J:91011 Kurokawa D, et al., Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development. 2004 Jul;131(14):3319-31
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6479847
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Reporter: lacZ
Direct Detection
Results
Specimen 1Bg: embryonic day 7.75; Otx2tm2.1Imat/Otx2+ (more )
Note: lateral view
Structure Level Pattern Image Note
TS11: future brain Present Regionally restricted 1Bg Expression is seen in the anterior neuroectoderm.

Specimen 1Bh: embryonic day 8.5; Otx2tm2.1Imat/Otx2+ (more )
Note: lateral view
Structure Level Pattern Image Note
TS13: future brain Present 1Bh

Specimen 1Bi: embryonic day 9.5; Otx2tm2.1Imat/Otx2+ (more )
Note: lateral view
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 1Bi The caudal limit of expression is the isthmus.
TS15: diencephalon Present 1Bi
TS15: future midbrain Present 1Bi

Specimen 1Bj: embryonic day 10.5; Otx2tm2.1Imat/Otx2+ (more )
Note: lateral view
Structure Level Pattern Image Note
TS17: brain Present Regionally restricted 1Bj The caudal limit of expression is the isthmus.
TS17: diencephalon Present 1Bj
TS17: midbrain Present 1Bj

Specimen 1Bl: embryonic day 10.5; Otx2tm2.1Imat/Otx2+ (more )
Note: frontal view
Structure Level Pattern Image Note
TS17: diencephalon Present 1Bl
TS17: midbrain Present 1Bl
TS17: telencephalon Present Regionally restricted 1Bl Expression is present in the ventral, but not dorsal, telencephalon.

Specimen 1Bp: embryonic day 10.5; Otx2tm2.1Imat/Otx2+ (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 1Bp Expression is present in the ventral, but not dorsal, telencephalon.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory