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Gene Expression Data
Assay Details
Assay
Reference: J:63629 Baas D, et al., The subcellular localization of OTX2 is cell-type specific and developmentally regulated in the mouse retina. Brain Res Mol Brain Res. 2000 May 31;78(1-2):26-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6479693
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Antibody: anti-Otx2
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: pigmented retinal epithelium Present 2A Expression is nuclear.
TS18: neural retina Absent 2A
Specimen 2B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present 2B
TS21: retina Present Single cells 2B
Specimen 2C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Present 2C
TS24: retina inner nuclear layer Present Single cells 2C
Specimen 2D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: pigmented retinal epithelium Present 2D
TS27: retina Present Diffuse 2D
Specimen 2E: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Strong Regionally restricted 2E Expression is in the outer portion of the inner nuclear layer.
TS28: pigmented retinal epithelium Present Regionally restricted 2E
Specimen 2F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 2F Expression is in the outer portion of the inner nuclear layer.
TS28: pigmented retinal epithelium Present 2F
Specimen 3A: embryonic day 16.0 (more )
Note: Double labeled: green - Otx2; red - Tubb3 (assay MGI:6479699).
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 3A Expression is in immature ganglion cells.
TS24: pigmented retinal epithelium Present 3A
Specimen 3B: postnatal adult (more )
Note: Double labeled: green - Otx2; red - Nefl (assay MGI:6479717).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3B Expression is absent in horizontal cells.
Specimen 3C: postnatal adult (more )
Note: Double labeled: green - Otx2; red - Stx1a (assay MGI:6479703).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3C Expression is absent in horizontal and amacrine cells.
Specimen 3D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3D Expression is in bipolar cells.
Specimen 3E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3E Expression is in the nuclei of bipolar cells.
TS28: pigmented retinal epithelium Present Regionally restricted 3E Expression is in the nuclei.
TS28: photoreceptor layer Present 3E Expression is in the cytoplasm.
Specimen 3F: postnatal adult (more )
Note: Double labeled: green - Otx2; red - Prkcg (assay MGI:6479705).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3F Expression is in rod and cone bipolar cells.
Specimen not shown: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: retina Present Diffuse Diffuse expression in the outer retina.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory