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Gene Expression Data
Assay Details
Assay
Reference: J:175263 Kenchegowda D, et al., Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells. Dev Biol. 2011 Aug 1;356(1):5-18
Assay type: RNA in situ
MGI Accession ID: MGI:6473828
Gene symbol: Klf5
Gene name: Kruppel-like transcription factor 5
Probe: Klf5 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1Ai: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cornea epithelium Weak 1Ai Low level of expression at embryonic stages. Expression largely confined to epithelial cells.
TS20: cornea stroma Trace 1Ai Low levels in stroma cells.

Specimen 1Aii: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cornea epithelium Present 1Aii Expression increased as development progressed. Expression largely confined to epithelial cells.
TS27: cornea stroma Weak 1Aii Low levels in stroma cells.

Specimen 1Aiii: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present 1Aiii Expression increased as development progressed. Expression largely confined to epithelial cells.
TS28: cornea stroma Weak 1Aiii Low levels in stroma cells.

Specimen 1Aiv: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present 1Aiv Expression increased as development progressed. Expression largely confined to epithelial cells.
TS28: cornea stroma Weak 1Aiv Low levels in stroma cells.

Specimen 1Av: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Strong 1Av Highest level of expression at PN20. Expression largely confined to epithelial cells.
TS28: cornea stroma Weak 1Av Low levels in stroma cells.

Specimen 1Bi: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: conjunctival sac Weak 1Bi Low level of expression at embryonic stages.

Specimen 1Bii: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: conjunctival sac Present 1Bii Expression gradually increased at postnatal stages.

Specimen 1Biii: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: conjunctival sac Present 1Biii Expression gradually increased at postnatal stages.

Specimen 1Biv: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: conjunctival sac Strong Regionally restricted 1Biv Relatively higher expression in forniceal epithelium at PN14 and PN20.

Specimen 1Bv: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: conjunctival sac Very strong 1Bv Highest level of expression at PN20.

Specimen 1Ci: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye epithelium Weak Regionally restricted 1Ci Low level of expression in eyelid at embryonic stages.

Specimen 1Cii: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: eyelid epithelium Weak Regionally restricted 1Cii Expression in palpebral epithelium.

Specimen 1Ciii: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: eyelid epithelium Present Regionally restricted 1Ciii Expression in palpebral epithelium.
TS27: meibomian gland Present 1Ciii
TS27: sebaceous gland Present 1Ciii

Specimen 1Civ: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: eyelid epithelium Present Regionally restricted 1Civ Expression in palpebral epithelium.
TS28: meibomian gland Present 1Civ
TS28: sebaceous gland Present 1Civ

Specimen 1Cv: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: eyelid epithelium Strong Regionally restricted 1Cv Highest level of expression at PN20. Expression more abundant in external palpebral epidermis compared with inner palpebral conjunctival epidermis.
TS28: meibomian gland Present 1Cv
TS28: sebaceous gland Present 1Cv


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory