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Gene Expression Data
Assay Details
Assay
Reference: J:160254 Urness LD, et al., FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol. 2010 Apr 15;340(2):595-604
Assay type: RNA in situ
MGI Accession ID: MGI:6473204
Gene symbol: Foxi2
Gene name: forkhead box I2
Probe: Foxi2 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3E: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: head surface ectoderm Present Regionally restricted 3E Expression marks prospective non-otic ectoderm. Authors report expression is a marker for cranial epidermis.
Specimen 3E1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: neural ectoderm Absent 3E1
Specimen 3E2: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: head surface ectoderm Present Regionally restricted 3E2 Expression marks prospective non-otic ectoderm. Authors report expression is a marker for cranial epidermis.
Specimen 3E3: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: neural ectoderm Absent 3E3
Specimen 3F: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: head surface ectoderm Present Regionally restricted 3F Expression expanded in mutant ectoderm.
Specimen 3F1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: head surface ectoderm Present Regionally restricted 3F1
Specimen 3F2: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: head surface ectoderm Strong 3F2 Expression more intense overall.
Specimen 3F3: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: head surface ectoderm Present Regionally restricted 3F3 Expression expanded posteriorly.
Specimen 3G: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: head surface ectoderm Present 3G
Specimen 3G1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: head surface ectoderm Present 3G1
Specimen 3G2: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: otic placode Absent 3G2 Expression excluded from otic cup.
Specimen 3G3: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: head surface ectoderm Present 3G3
Specimen 3H: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: head surface ectoderm Present Regionally restricted 3H Expression throughout an inappropriately enlarged ectoderml domain.
Specimen 3H1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: head surface ectoderm Present Regionally restricted 3H1 Expression throughout dorsal ectoderm.
Specimen 3H2: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: otic pre-placode Trace Regionally restricted 3H2 Some expression encroached into thickened region of small ventrally-located otic cup-like structure.
Specimen 3H3: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 11-12 somite stage
Structure Level Pattern Image Note
TS13: head surface ectoderm Present Regionally restricted 3H3 Expression throughout dorsal ectoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory