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Gene Expression Data
Assay Details
Assay
Reference: J:160254 Urness LD, et al., FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol. 2010 Apr 15;340(2):595-604
Assay type: RNA in situ
MGI Accession ID: MGI:6473202
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf4 probe39
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic pre-placode Present Regionally restricted 3A Expression in restricted portion of prospective placode.
TS12: non-neural ectoderm Present Regionally restricted 3A Expression in ventral ectoderm.

Specimen 3A1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic pre-placode Present Regionally restricted 3A1 Expression in restricted portion of prospective placode.
TS12: non-neural ectoderm Present Regionally restricted 3A1 Expression in ventral ectoderm.
TS12: branchial arch endoderm Absent 3A1

Specimen 3B: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic pre-placode Absent 3B Expression absent from dorsal ectoderm.
TS12: non-neural ectoderm Present Regionally restricted 3B Expression unchanged in ventral ectoderm.

Specimen 3B1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7-8 somite stage
Structure Level Pattern Image Note
TS12: otic pre-placode Absent 3B1 Expression absent from dorsal ectoderm.
TS12: non-neural ectoderm Present Regionally restricted 3B1 Expression unchanged in ventral ectoderm.
TS12: branchial arch endoderm Present 3B1 Expression upregulated in pharyngeal endoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory