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Gene Expression Data
Assay Details
Assay
Reference: J:160254 Urness LD, et al., FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol. 2010 Apr 15;340(2):595-604
Assay type: RNA in situ
MGI Accession ID: MGI:6473195
Gene symbol: Spry1
Gene name: sprouty RTK signaling antagonist 1
Probe: Spry1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1E left: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1E left Expression domain includes but is larger than the prospective otic placode.
TS12: otic pre-placode Present 1E left
Specimen 1E right: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Weak Regionally restricted 1E right Expression strongly reduced in dorsal (presumptive otic) portion of ectoderm.
Specimen 1E1: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10+, Fgf3tm1.1Sms/Fgf3+ (more )
Note: 7 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1E1 Expression domain includes but is larger than the prospective otic placode.
TS12: otic pre-placode Present 1E1
Specimen 1E2: embryonic day 8.5; Fgf10tm1.1Sms/Fgf10tm1.1Sms, Fgf3tm1.1Sms/Fgf3tm1.1Sms (more )
Note: 7 somite stage
Structure Level Pattern Image Note
TS12: otic pre-placode Trace Regionally restricted 1E2 Expression strongly reduced in dorsal (presumptive otic) portion of ectoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory