Gene Expression Data
Assay Details
Assay
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Reference:
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J:173632
Hakanen J, et al., Netrin1 is required for neural and glial precursor migrations into the olfactory bulb. Dev Biol. 2011 Jul 1;355(1):101-14
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6472876
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Gene symbol:
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Ntn1
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Gene name:
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netrin 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1D:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1G:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Specimen
1L:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
1M:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS28: lateral ventricle ependyma |
Strong |
Regionally restricted |
1M
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Expression confined to one continuous later of cells next to ventricle lumen, corresponding to ependymal cells.
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TS28: brain ependyma |
Present |
Regionally restricted |
1M
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Expression in ependymal cells of more caudal brain regions.
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Specimen
7A:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
7B:
(close )
Specimen
7C:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Specimen
7D:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS27: rostral migratory stream |
Present |
Regionally restricted |
7D
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At all stages analyzed, expressing cells did not reach as far distally from ventricular zone as in controls. Expressing cells spread in a more broad area in proximal part of horizontal rostral migratory stream close to the ventricular zone.
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TS27: main olfactory bulb |
Absent |
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7D
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Specimen
7E:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * ICR
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Mutant Allele(s):
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Ntn1Gt(IRESBetageo)1Pgr/Ntn1+
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Specimen
7F:
(close )
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