About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:110696 Gonzalez MA, et al., Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev. 2006 Jul 15;20(14):1880-4
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6470690
Gene symbol: Cdkn1c
Gene name: cyclin dependent kinase inhibitor 1C
Results
Specimen S5 WT: embryonic day 3.5 (more )
Note: Double labeled: green - p57Kip2 (Cdkn1c); red - Geminin (Gmnn assay MGI:6470686).
Structure Level Pattern Image Note
TS4: blastocyst Present S5_WT p57Kip2 Geminin

Specimen S5 Mutant: embryonic day 3.5; GmnnGt(XT0615)Wtsi/GmnnGt(XT0615)Wtsi (more )
Note: Double labeled: green - p57Kip2 (Cdkn1c); red - Geminin (Gmnn assay MGI:6470686).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted S5_Mutant p57Kip2 Geminin Authors report expression enriched in most nuclei of mutant embryos.

Specimen S5 Optical section (left): embryonic day 3.5; GmnnGt(XT0615)Wtsi/GmnnGt(XT0615)Wtsi (more )
Note: Double labeled: green - p57Kip2 (Cdkn1c); red - Geminin (Gmnn assay MGI:6470686).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted S5_Optical section (left) Authors report expression enriched in most nuclei of mutant embryos.

Specimen S5 Optical section (middle): embryonic day 3.5; GmnnGt(XT0615)Wtsi/GmnnGt(XT0615)Wtsi (more )
Note: Double labeled: green - p57Kip2 (Cdkn1c); red - Geminin (Gmnn assay MGI:6470686).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted S5_Optical section (middle) Authors report expression enriched in most nuclei of mutant embryos.

Specimen S5 Optical section (right): embryonic day 3.5; GmnnGt(XT0615)Wtsi/GmnnGt(XT0615)Wtsi (more )
Note: Double labeled: green - p57Kip2 (Cdkn1c); red - Geminin (Gmnn assay MGI:6470686).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted S5_Optical section (right) Authors report expression enriched in most nuclei of mutant embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory