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Gene Expression Data
Assay Details
Assay
Reference: J:177133 Mehta V, et al., Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract. Dev Dyn. 2011 Nov;240(11):2548-60
Assay type: RNA in situ
MGI Accession ID: MGI:6470445
Gene symbol: Axin2
Gene name: axin 2
Probe: CVprobeAxin2(0203)
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 17.5 (more )
Note: Labeling was visualized using BM purple. The specimen was also stained for Cdh1 (red) to visualize the urothelium and Acta2 (green) to visualize the muscularis mucosa and muscularis propria.
Structure Level Pattern Image Note
TS25: lamina propria of pelvic urethra of female Strong 3A
TS25: basal cell layer of pelvic urethra of female Weak 3A Expression levels are weaker in females compared to males.
Specimen 3B: embryonic day 17.5 (more )
Note: Labeling was visualized using BM purple. The specimen was also stained for Cdh1 (red) to visualize the urothelium and Acta2 (green) to visualize the muscularis mucosa and muscularis propria.
Structure Level Pattern Image Note
TS25: epithelium of seminal vesicle Strong 3B
TS25: lamina propria of seminal vesicle Strong 3B Expression is present in the mesenchyme.
TS25: lamina propria of pelvic urethra of male Strong 3B
TS25: basal cell layer of pelvic urethra of male Strong Regionally restricted 3B Expression is present in the cranial-most aspect of the pelvic urethra.
TS25: prostate epithelium Strong 3B
TS25: muscle layer of pelvic urethra of male Weak 3B
Specimen 3C: postnatal day 5 (more )
Note: Labeling was visualized using BM purple. The specimen was also stained for Cdh1 (red) to visualize the urothelium and Acta2 (green) to visualize the muscularis mucosa and muscularis propria.
Structure Level Pattern Image Note
TS28: prostate epithelium Present 3C Expression is present in elongating prostatic bud epithelium.
TS28: lamina propria of pelvic urethra of male Absent 3C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory