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Gene Expression Data
Assay Details
Assay
Reference: J:282332 Okamura E, et al., Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos. Dev Biol. 2019 Nov 15;455(2):382-392
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6469513
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Assay notes: E7.75 embryos were from natural mated females.
Results
Specimen 5A Sox2 +/+: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS11: primordial germ cell Present 5A Sox2 +/+
Specimen 5A Sox2 +/-: embryonic day 7.75; Esrrbtm1Vgi/Esrrb+ (more )
Structure Level Pattern Image Note
TS11: primordial germ cell Present 5A Sox2 +/-
Specimen 5A Sox2 -/-: embryonic day 7.75; Esrrbtm1Vgi/Esrrbtm1Vgi (more )
Structure Level Pattern Image Note
TS11: primordial germ cell Weak 5A Sox2 -/- Number of expressing cells significantly decreased compared to wild-type and heterozygous embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory