Gene Expression Data
Assay Details
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Assay
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Reference:
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J:270314
Mitomo K, et al., Sphenoid bone hypoplasia is a skeletal phenotype of cleidocranial dysplasia in a mouse model and patients. Bone. 2019 Mar;120:176-186
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6468212
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Gene symbol:
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Sp7
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Gene name:
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Sp7 transcription factor 7
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Results
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Specimen
1G:
embryonic day 14.5
(more )
Specimen
1G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: sphenoid bone |
Present |
Scattered |
1G
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Positive cells are scattered throughout the region of mesenchymal cell condensation in the medial pterygoid process region of sphenoid bone.
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Specimen
1H:
embryonic day 14.5; Runx2tm1Kish/Runx2 +
(more )
Specimen
1H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: sphenoid bone |
Present |
Single cells |
1H
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There are a few scattered positive cells in the medial pterygoid process region of sphenoid bone.
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Specimen
2G:
embryonic day 15.5
(more )
Specimen
2G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: sphenoid bone |
Present |
Scattered |
2G
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Positive cells are scattered around the osteoid, and small flattened cells are located at the cranial region of mesenchymal-cell condensation.
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Specimen
2H:
embryonic day 15.5; Runx2tm1Kish/Runx2 +
(more )
Specimen
2H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: sphenoid bone |
Present |
Single cells |
2H
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There are a few positive cells scattered at the cranial region of mesenchymal-cell condensation.
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Specimen
3G:
embryonic day 16.5
(more )
Specimen
3G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: sphenoid bone |
Present |
Scattered |
3G
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Positive cells are scattered around the trabecular bones and the cartilage at the lower part of the medial pterygoid process region.
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Specimen
3H:
embryonic day 16.5; Runx2tm1Kish/Runx2 +
(more )
Specimen
3H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: sphenoid bone |
Present |
Regionally restricted |
3H
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Positive cells were seen beneath the cartilage and at the medial pterygoid process.
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Specimen
4G:
embryonic day 18.5
(more )
Specimen
4G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: sphenoid bone |
Present |
Regionally restricted |
4G
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Positive cells are scattered in two-thirds of the cranial side of the medial pterygoid process around the trabecular bones and beneath the cartilage in the lower part of the medial pterygoid process region.
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Specimen
4H:
embryonic day 18.5; Runx2tm1Kish/Runx2 +
(more )
Specimen
4H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: sphenoid bone |
Present |
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4H
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Positive cells are distributed at the central area in osteoid-like tissue and beneath the cartilage of the medial pterygoid process region.
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