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Gene Expression Data
Assay Details
Assay
Reference: J:237308 Biosse Duplan M, et al., Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible. Hum Mol Genet. 2016 Jul 15;25(14):2997-3010
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6468056
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Results
Specimen 2A WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: Meckel's cartilage Present Regionally restricted 2A WT Ki67 left , 2A WT Ki67 right Expression is in proliferating cells.
Specimen 2A Fgfr3Y367C/-: embryonic day 16.5; Fgfr3tm1Llm/Fgfr3+ (more )
Structure Level Pattern Image Note
TS24: Meckel's cartilage Present Regionally restricted 2A +/- Ki67 left , 2A +/- Ki67 right The number of proliferating cells has increased in this mutant compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory