About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:62920 Grimmond S, et al., Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development. Hum Mol Genet. 2000 Jun 12;9(10):1553-60
Assay type: RNA in situ
MGI Accession ID: MGI:6467421
Gene symbol: Serpine2
Gene name: serine (or cysteine) peptidase inhibitor, clade E, member 2
Probe: IMAGE clone 1764633
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2a (left): embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: primary sex cord Strong 2a (left) Prominent expression restricted to testis cords.
Specimen 2a (right): embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: ovary Absent 2a (right)
Specimen 2b (left): embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ovary Absent 2b (left)
Specimen 2b (right): embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: primary sex cord Strong 2b (right) Prominent expression in testis cords.
Specimen 2c: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: gonad Present 2c Expression restricted to male gonad.
Specimen 2d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: urogenital ridge Absent 2d
Specimen 2e (left): embryonic day 11.25 (more )
Structure Level Pattern Image Note
TS19: urogenital ridge Present 2e (left) Expression first observed at ~11.25 dpc (15 tail-somite stage).
Specimen 2e (right): embryonic day 11.25 (more )
Structure Level Pattern Image Note
TS19: urogenital ridge Absent 2e (right)
Specimen 2f: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: Sertoli cell Sertoli cell Strong 2f Prominent Sertoli cell expression.
TS21: primary sex cord Strong Regionally restricted 2f Expression throughout testis cord, with highest level at periphery where Sertoli cells abut basement membrane.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory