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Gene Expression Data
Assay Details
Assay
Reference: J:292838 Iulianella A, et al., The Hedgehog receptor Patched1 regulates proliferation, neurogenesis, and axon guidance in the embryonic spinal cord. Mech Dev. 2019 Dec;160:103577
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6467286
Gene symbol: Shh
Gene name: sonic hedgehog
Antibody: 5E1
Results
Specimen 1D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain floor plate Present 1D
TS15: notochord Present 1D
Specimen 1E: embryonic day 9.5; Ptch1wig/Ptch1wig (more )
Structure Level Pattern Image Note
TS15: future hindbrain floor plate Present Regionally restricted 1E Expression expanded from floor plate, especially in more anterior regions of neural tube.
TS15: notochord Present 1E
Specimen 1H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube floor plate Present 1H
TS15: notochord Present 1H
Specimen 1I: embryonic day 9.5; Ptch1wig/Ptch1wig (more )
Structure Level Pattern Image Note
TS15: neural tube floor plate Present Regionally restricted 1I Expression expanded from floor plate.
Specimen 5A: embryonic day 10.5 (more )
Note: Triple labeled: green - Shh; red - Tag-1 (Cntn2 assay MGI:6467295); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present 5A
Specimen 5B: embryonic day 10.5; Ptch1wig/Ptch1wig (more )
Note: Triple labeled: green - Shh; red - Tag-1 (Cntn2 assay MGI:6467295); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5B Authors report aberrant dorsal exit of ventral motor roots and reduced crossing of commissural fibers in ventral commissure.
Specimen 5C: embryonic day 10.5 (more )
Note: Triple labeled: green - Shh; red - Tag-1 (Cntn2 assay MGI:6467295); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present 5C
Specimen 5D: embryonic day 10.5; Ptch1wig/Ptch1wig (more )
Note: Triple labeled: green - Shh; red - Tag-1 (Cntn2 assay MGI:6467295); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5D Aberrant targeting of commissural axons towards floorplate. Dorsal exit of ventral root.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory