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Gene Expression Data
Assay Details
Assay
Reference: J:173580 Hovorakova M, et al., Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor. J Exp Zool B Mol Dev Evol. 2011 Jul 15;316(5):347-58
Assay type: RNA in situ
MGI Accession ID: MGI:6466968
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe180
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: tooth Present Regionally restricted 5A Expression is in the prospective incisor region.
TS20: dental placode Present 5A Expression is in the anterior part of each lower jaw quadrant. In the cheek region, a small area of expression corresponds to the molar anlage.
Specimen 5C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: dental placode Present Regionally restricted 5C Expression is in the epithelial budding in two side by side domains in each lower jaw quadrant.
Specimen 5F: embryonic day 13.5 (more )
Note: This is a developmentally less advanced embryo.
Structure Level Pattern Image Note
TS21: dental placode Present Regionally restricted 5F Expression is in the epithelial budding in a domain in each lower jaw quadrant.
TS21: incisor Present Regionally restricted 5F Expression is at the base of the incisor bud.
Specimen 5I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dental placode Present Regionally restricted 5I Expression is in the epithelial budding in a domain in each lower jaw quadrant.
Specimen 5L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dental placode Present Regionally restricted 5L Expression is in the epithelial budding in a small domain in each lower jaw quadrant.
TS21: lower jaw incisor Present Regionally restricted 5L Expression is at the tip of the incisor bud.
TS21: lower jaw Weak Regionally restricted 5L There is weak expression between the anterior and posterior expression doamins.
Specimen 5O: embryonic day 13.5 (more )
Note: This is a developmentally most advanced embryo.
Structure Level Pattern Image Note
TS21: lower jaw incisor Present Regionally restricted 5O Expression is at the tip of the incisor bud.
Specimen 6B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: upper jaw Present Regionally restricted 6B There are two expression domains in the anterior region.
TS21: upper jaw incisor Present 6B
Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mandible primordium Present Regionally restricted Expression is in a narow band that extends laterodistally.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory