Msx1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:72150 Gong SG, Phenotypic and molecular analyses of A/WySn mice. Cleft Palate Craniofac J. 2001 Sep;38(5):486-91
Assay type:	RNA in situ
MGI Accession ID:	MGI:6466573
Gene symbol:	Msx1
Gene name:	msh homeobox 1

Probe:	Msx1 probe45
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 4a: embryonic day 10.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)

Structure	Level	Image	Note
TS17: 1st branchial arch maxillary component	Present	4a	Relatively low expression. Similar expression in all embryos examined.
TS17: latero-nasal process	Present	4a	Relatively low expression. Similar expression in all embryos examined.
TS17: medial-nasal process	Present	4a	Relatively low expression. Similar expression in all embryos examined.

Specimen 4b: embryonic day 10.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)

Structure	Level	Image	Note
TS17: 1st branchial arch maxillary component	Present	4b	Relatively low expression. Similar expression in all embryos examined.
TS17: latero-nasal process	Present	4b	Relatively low expression. Similar expression in all embryos examined.
TS17: medial-nasal process	Present	4b	Relatively low expression. Similar expression in all embryos examined.

Specimen 4c: embryonic day 11.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: non-clefted

Structure	Level	Pattern	Image	Note
TS19: medial-nasal process	Strong	Regionally restricted	4c	Expressed in the distal growing tips. Expression was decreased from the site of fusion.
TS19: nasal pit	Strong	Regionally restricted	4c	Expressed in the superior and superior-medial portions.
TS19: latero-nasal process	Present	Regionally restricted	4c	Expression was decreased from the site of fusion.
TS19: maxillary process	Present	Regionally restricted	4c	Expression was decreased from the site of fusion.

Specimen 4d: embryonic day 12.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: non-clefted

Structure	Level	Pattern	Image	Note
TS20: medial-nasal process	Present	Regionally restricted	4d	Expressed in the distal growing tips. Expression was decreased to low from the site of fusion.
TS20: nasal septum	Weak		4d

Specimen 4e: embryonic day 13.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: non-clefted

Structure	Level	Pattern	Image	Note
TS21: oral cavity	Present	Regionally restricted	4e	Expressed around the lip.
TS21: nasal cavity	Present	Regionally restricted	4e	Expressed surrounding the edges.

Specimen 4f: embryonic day 11.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: non-clefted

Structure	Level	Pattern	Image	Note
TS19: medial-nasal process	Strong	Regionally restricted	4f	Expressed in the distal growing tips. Expression was decreased from the site of fusion.
TS19: nasal pit	Strong	Regionally restricted	4f	Expressed in the superior and superior-medial portions.

Specimen 4g: embryonic day 12.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: non-clefted

Structure	Level	Pattern	Image	Note
TS20: nasal septum	Weak		4g
TS20: medial-nasal process	Present	Regionally restricted	4g	Expressed in the distal growing tips. Expression was decreased to low from the site of fusion.
TS20: nasal cavity	Strong	Regionally restricted	4g	Expressed in the superior and superior-medial portions.

Specimen 4h: embryonic day 13.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: non-clefted

Structure	Level	Pattern	Image	Note
TS21: oral cavity	Present	Regionally restricted	4h	Expressed around the lip.
TS21: nasal cavity	Present	Regionally restricted	4h	Expressed surrounding the edges.

Specimen 4i: embryonic day 11.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: clefted

Structure	Level	Pattern	Image	Note
TS19: medial-nasal process	Strong	Regionally restricted	4i	Expressed in the distal growing tips.
TS19: latero-nasal process	Strong	Regionally restricted	4i	Exprssed in the lateral borders.
TS19: maxillary process	Strong	Regionally restricted	4i	Exprssed in the lateral borders.
TS19: nasal pit	Strong	Regionally restricted	4i	Expressed in the superior and medial portions.

Specimen 4j: embryonic day 12.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: clefted

Structure	Level	Pattern	Image	Note
TS20: medial-nasal process	Strong	Regionally restricted	4j	Expressed in the distal growing tips.
TS20: latero-nasal process	Strong	Regionally restricted	4j	Exprssed in the lateral borders.
TS20: maxillary process	Strong	Regionally restricted	4j	Exprssed in the lateral borders.
TS20: nasal cavity	Strong	Regionally restricted	4j	Expressed in the superior and medial portions.

Specimen 4k: embryonic day 13.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: clefted

Structure	Level	Pattern	Image	Note
TS21: nasal cavity	Strong	Regionally restricted	4k	Expression surrounding the superior portion had decreased but relatively higher compared with that of no cleft. The expression on the palatal half remained high.

Specimen 4l: embryonic day 11.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: clefted

Structure	Level	Pattern	Image	Note
TS19: latero-nasal process	Strong	Regionally restricted	4l	Expressed in the distal growing tips.
TS19: medial-nasal process	Strong	Regionally restricted	4l	Expressed in the distal growing tips.

Specimen 4m: embryonic day 12.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: clefted

Structure	Level	Pattern	Image	Note
TS20: latero-nasal process	Strong	Regionally restricted	4m	Expressed in the distal growing tips.
TS20: medial-nasal process	Strong	Regionally restricted	4m	Expressed in the distal growing tips.

Specimen 4n: embryonic day 13.5; Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1 (more

)
Note: clefted

Structure	Level	Pattern	Image	Note
TS21: nasal cavity	Strong	Regionally restricted	4n	Decreased expression in the facial side of the the facial processes. The expression on the palatal half remained high.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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