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Gene Expression Data
Assay Details
Assay
Reference: J:259674 Xu W, et al., Delta-like 2 negatively regulates chondrogenic differentiation. J Cell Physiol. 2018 Sep;233(9):6574-6582
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6460445
Gene symbol: Dlk2
Gene name: delta like non-canonical Notch ligand 2
Antibody: anti-DLK-2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 9a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future leg mesenchyme Weak Regionally restricted 9a Weak intracellular expression in central regions of mesenchymal condensations.
Specimen 9a inset: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future leg mesenchyme Weak Regionally restricted 9a inset Weak intracellular expression in central regions of mesenchymal condensations.
Specimen 9b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hindlimb cartilage condensation Present Regionally restricted 9b Expression in both immature and mature/hypertrophic chondrocytes. Chondrocyte maturation gradient from superficial zone to hypertrophic zone.
Specimen 9c: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hindlimb cartilage condensation Present Regionally restricted 9c Expression in both immature and mature/hypertrophic chondrocytes. Chondrocyte maturation gradient from superficial zone to hypertrophic zone.
Specimen 9d: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hindlimb long bone Present Regionally restricted 9d Expression in both immature and mature/hypertrophic chondrocytes. Chondrocyte maturation gradient from superficial zone to hypertrophic zone.
Specimen 9e: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: articular cartilage Present Regionally restricted 9e Expression in immature chondrocytes in superfical zones of articular cartilage.
Specimen 9f: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: articular cartilage Weak Regionally restricted 9f Expression in superficial zones became weaker.
Specimen 9g: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: articular cartilage Weak Regionally restricted 9g Expression in superficial zones became weaker.
Specimen 9h: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epiphyseal plate hypertrophic zone Present Regionally restricted 9h Expression in mature/hypertrophic chondrocytes.
Specimen 9i: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate hypertrophic zone Present Regionally restricted 9i Expression in hypertrophic zones showed no change.
Specimen 9j: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate hypertrophic zone Present Regionally restricted 9j Expression in hypertrophic zones showed no change.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory