Map1lc3b Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:270838 Wiederstein JL, et al., Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown. Cell Rep. 2018 May 1;23(5):1342-1356
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6458592
Gene symbol:	Map1lc3b
Gene name:	microtubule-associated protein 1 light chain 3 beta

Antibody:	anti-LC3 (#2775)
Detection system:	Alexa Fluor

Results

Specimen S3C LC3 wild-type: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: soleus	Present		S3C LC3 wild type

Specimen S3C LC3 Mettl21c -/-: postnatal adult; Mettl21c^tm1.1Krug/Mettl21c^tm1.1Krug (more

)

Structure	Level	Pattern	Image	Note
TS28: soleus	Strong		S3C LC3 Mettl21c -/-	Authors report upregulation of expression.

S3D LC3 ©

S3D Merge ©

Specimen S3D LC3: postnatal adult (more

)
Note: Double labeled: red - Map1lc3a (LC3); blue - Myh7 (assay MGI:6458580).

Structure	Level	Pattern	Image	Note
TS28: soleus	Present	Regionally restricted	S3D LC3 , S3D Merge	Expression in slow muscle fibers.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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