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Gene Expression Data
Assay Details
Assay
Reference: J:166548 Schaller F, et al., A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene. Hum Mol Genet. 2010 Dec 15;19(24):4895-905
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6458158
Gene symbol: Oxt
Gene name: oxytocin
Antibody: anti-OT(VA-10)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Newborns (3-5 h after birth).
Results
Specimen 2A WT: postnatal day 0 (more )
Note: Double labeled: green - Oxt (VA10 antibody; red - Oxt (PS38 antibody; assay MGI:6458155).
Structure Level Pattern Image Note
TS27: paraventricular hypothalamic nucleus Present 2A WT Merge , 2A WT VA10
Specimen 2A KO: postnatal day 0; Magel2tm1.1Mus/Magel2+ (more )
Note: Paternally inherited allele. Double labeled: green - Oxt (VA10 antibody; red - Oxt (PS38 antibody; assay MGI:6458155).
Structure Level Pattern Image Note
TS27: paraventricular hypothalamic nucleus Strong 2A KO VA10 , 2A KO Merge There is a 1.7-fold increase in the detection of intermediate form compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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