About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:103362 Nakamura H, et al., Developmentally regulated expression of Sp1 in the mouse cornea. Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4092-6
Assay type: RNA in situ
MGI Accession ID: MGI:6456782
Gene symbol: Sp1
Gene name: trans-acting transcription factor 1
Probe: Sp1 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Table 1 - E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Weak Regionally restricted Expression observed in the lens epithelium.

Specimen 2/Table 1 - E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cornea epithelium Moderate 2_E12.5 Expression observed in the ectoderm.
TS20: cornea stroma Moderate 2_E12.5 Expression observed in the mesenchyme.
TS20: lens vesicle epithelium Weak 2_E12.5

Specimen 2/Table 1 - E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cornea epithelium Strong 2_E15.5
TS23: cornea stroma Strong 2_E15.5
TS23: lens epithelium Trace 2_E15.5

Specimen Table 1 - E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cornea epithelium Moderate
TS26: cornea stroma Moderate
TS26: lens epithelium Trace Staining very faint or absent.

Specimen Table 1 - P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cornea epithelium Moderate
TS27: cornea stroma Moderate
TS27: cornea endothelium Absent
TS27: lens epithelium Trace Staining very faint or absent.

Specimen Table 1 - P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Moderate
TS28: cornea stroma Moderate
TS28: cornea endothelium Trace
TS28: lens epithelium Trace Staining very faint or absent.

Specimen 2/Table 1 - P11: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Moderate 2_P11
TS28: cornea stroma Moderate 2_P11
TS28: cornea endothelium Weak 2_P11 Staining weak or moderate.
TS28: lens epithelium Weak 2_P11

Specimen 2/Table 1 - P15: postnatal day 15 (more )
Note: eyelid opening occurs at P13-14
Structure Level Pattern Image Note
TS28: cornea epithelium Weak 2_P15 At this age expression in the basal corneal epithelial cells and karatocytes is much reduced.
TS28: cornea stroma Weak 2_P15
TS28: cornea endothelium Trace 2_P15
TS28: lens epithelium Trace 2_P15 Staining very faint or absent.

Specimen Table 1 - P30: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Trace
TS28: cornea stroma Weak
TS28: cornea endothelium Trace
TS28: lens epithelium Trace Staining very faint or absent.

Specimen 2/Table 1 - P60: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Trace 2_P60
TS28: cornea stroma Weak 2_P60
TS28: cornea endothelium Trace 2_P60
TS28: lens epithelium Trace 2_P60 Staining very faint or absent.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory