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Gene Expression Data
Assay Details
Assay
Reference: J:37095 Orioli D, et al., Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49
Assay type: RNA in situ
MGI Accession ID: MGI:6455088
Gene symbol: Ephb3
Gene name: Eph receptor B3
Probe: Sek4 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forebrain ventricular layer Present 4A With the highest levels in the region closest to the midline.
TS21: forebrain Present Regionally restricted 4A Expressed in the intermediate zone, with the highest levels in the region closest to the midline.
TS21: neocortex Present Regionally restricted 4A Highest expression in cingulate cortex.
TS21: telencephalon Present Regionally restricted 4A Highest expression in the hippocampal anlage.
TS21: diencephalon Present Regionally restricted 4A Highest expression in the ventral aspect of the third ventricle, through which the anterior commissure axons will travel on their way to the contralateral side.

Specimen 4C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 4C Highest expression.
TS24: cerebral cortex ventricular layer Present 4C Highest expression.
TS24: cortical plate Present 4C Highest expression.
TS24: cerebral cortex intermediate zone Absent 4C

Specimen 6E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: medial habenular nucleus Strong 6E
TS22: lateral habenular nucleus Present 6E

Specimen 8E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mandible Present 8E
TS21: maxilla Present 8E
TS21: tongue Present 8E
TS21: palatal shelf Present Regionally restricted 8E Expressed in the vertical palatal shelves.
TS21: face mesenchyme Strong 8E

Specimen 8F: embryonic day 13.5; Ephb3tm1Kln/Ephb3tm1Kln (more )
Structure Level Pattern Image Note
TS21: face mesenchyme Absent 8F
TS21: mandible Absent 8F
TS21: maxilla Absent 8F
TS21: palatal shelf Absent 8F
TS21: tongue Absent 8F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory