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Gene Expression Data
Assay Details
Assay
Reference: J:37095 Orioli D, et al., Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6455072
Gene symbol: Cntn2
Gene name: contactin 2
Antibody: Anti-Tag1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: corpus callosum Present 3C
TS27: hippocampal commissure Present 3C

Specimen 3D: postnatal day 0; Ephb2tm1Paw/Ephb2tm1Paw, Ephb3tm1Kln/Ephb3tm1Kln (more )
Structure Level Pattern Image Note
TS27: hippocampal commissure Present 3D
TS27: intercerebral commissure Present Regionally restricted 3D Expressed in Probst's bundles, callosal axons finding an alternative path via the hippocampal commissure.

Specimen 5I: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 5I Expressed in the most anterior part.

Specimen 5J: postnatal day 0; Ephb2tm1Paw/Ephb2tm1Paw, Ephb3tm1Kln/Ephb3tm1Kln (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 5J Expressed in the most anterior part, but less well bundled compared with the wild-type.

Specimen 7C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: diencephalon Present Regionally restricted 7C Expressed in tightly bundled habenular-interpeduncular tract axons.

Specimen 7D: postnatal day 0; Ephb2tm1Paw/Ephb2tm1Paw, Ephb3tm1Kln/Ephb3tm1Kln (more )
Structure Level Pattern Image Note
TS27: diencephalon Present Regionally restricted 7D Expressed in very short and loosely packed fibre bundled habenular-interpeduncular tract axons.

Specimen not shown: postnatal day 0; Ephb2tm1Paw/Ephb2tm1Paw, Ephb3tm1Kln/Ephb3tm1Kln (more )
Structure Level Pattern Image Note
TS27: diencephalon Present Regionally restricted In contrast to commissural axons, the longitudinal habenular-interpeduncle tract axons did not show a defect in guidance.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory