About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:223183 Yang T, et al., Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Mol Genet Genomic Med. 2014 Mar;2(2):138-51
Assay type: RNA in situ
MGI Accession ID: MGI:6449683
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 cDNA38
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5E
Specimen 5E': embryonic day 13.5 (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Absent 5E' Expression is seen in the posterior (but not anterior) palate.
TS21: palatal shelf epithelium Absent 5E'
Specimen 5E'': embryonic day 13.5 (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 5E'' Expression is seen in the posterior palate.
TS21: palatal shelf epithelium Absent 5E''
Specimen 5F: embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5F Expression is unaffected in the mutant.
Specimen 5F': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Absent 5F' As in wild type, expression is seen in the posterior (but not anterior) palate.
TS21: palatal shelf epithelium Absent 5F'
Specimen 5F'': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 5F'' Expression is seen in the posterior palate; it is unaffected in the mutant.
TS21: palatal shelf epithelium Absent 5F''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory