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Gene Expression Data
Assay Details
Assay
Reference: J:229352 Metzger DE, et al., Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic beta-cells while repressing alpha-cell functions. Diabetes. 2014 May;63(5):1804-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441171
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2A +/+: embryonic day 17.5 (more )
Note: Double labeled: green - Gcg; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS25: pancreas Present 2A left Expressed in alpha-cells.
Specimen 2A +/-: embryonic day 17.5; Tle3tm1Jcc/Tle3+ (more )
Note: Double labeled: green - Gcg; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS25: pancreas Present 2A right An increase in glucagon-positive alpha-cells and bihormonal insulin-positive/glucagon-positive cells.
Specimen 2C +/+: postnatal week 6 (more )
Note: Double labeled: green - Gcg; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 2C left Expressed in alpha-cells.
Specimen 2C +/-: postnatal week 6; Tle3tm1Jcc/Tle3+ (more )
Note: Double labeled: green - Gcg; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 2C right An increase in glucagon-positive alpha-cells and bihormonal insulin-positive/glucagon-positive cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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