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Gene Expression Data
Assay Details
Assay
Reference: J:86824 Payer B, et al., stella is a maternal effect gene required for normal early development in mice. Curr Biol. 2003 Dec 2;13(23):2110-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6438140
Gene symbol: Dppa3
Gene name: developmental pluripotency-associated 3
Antibody: Anti-Stella
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: secondary oocyte Present 1C , 1A Expression was excluded from condensed metaphase chromosomes.
Specimen 1D: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 1F , 1D Expression was localized to the cytoplasm and pronuclei.
Specimen 1G: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 1I , 1G Expression was localized to the cytoplasm and nucleus.
Specimen 1J: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1L , 1J Expression was localized to the cytoplasm and nucleus.
Specimen 1M: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present 1O , 1M Expression was localized to the cytoplasm and nucleus.
Specimen 5A/B: embryonic day 1.5; Dppa3tm1Masu/Dppa3+ (more )
Note: Embryo from mating between heterozygous females and homozygous males.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 5A/B Maternal and zygotic expression.
Specimen 5C/D: embryonic day 2.5; Dppa3tm1Masu/Dppa3+ (more )
Note: Embryo from mating between heterozygous females and homozygous males.
Structure Level Pattern Image Note
TS3: early embryo Present 5C/D Maternal and zygotic expression.
Specimen 5E/F: embryonic day 1.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Note: Embryo from mating between heterozygous females and homozygous males.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 5E/F Maternal expression only.
Specimen 5G/H: embryonic day 2.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Note: Embryo from mating between heterozygous females and homozygous males.
Structure Level Pattern Image Note
TS3: compacted morula Weak 5G/H Mutant embryos with only maternal expression do not show much staining from E2.5 onwards. Maternally inherited Dppa3 was degraded by the early morula stage.
Specimen 5I/J: embryonic day 3.5; Dppa3tm1Masu/Dppa3+ (more )
Note: Embryo from mating between homozygous females and wild-type males.
Structure Level Pattern Image Note
TS4: compacted morula Present 5I/J Expression from the paternal allele was clearly detected.
Specimen 5K/L: embryonic day 1.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Note: Embryo from mating between homozygous intercross.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Absent 5K/L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory