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Gene Expression Data
Assay Details
Assay
Reference: J:199462 Probst S, et al., The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30
Assay type: RNA in situ
MGI Accession ID: MGI:6438082
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2 probe13
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3C Wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: radius-ulna pre-cartilage condensation Present 3C Wt Expression domains mark radius and ulna primordia.
Specimen 3C Gli3delta/delta: embryonic day 12.5; Gli3tm1.2Zllr/Gli3tm1.2Zllr (more )
Structure Level Pattern Image Note
TS20: radius-ulna pre-cartilage condensation Weak 3C Gli3delta/delta Expression slightly reduced. compared to wild type.
Specimen 3C Vlkdelta/delta: embryonic day 12.5; Pkdcctm1.2Azun/Pkdcctm1.2Azun (more )
Structure Level Pattern Image Note
TS20: radius-ulna pre-cartilage condensation Present 3C Vlkdelta/delta
Specimen 3C Vlkdelta/delta Gli3delta/delta: embryonic day 12.5; Gli3tm1.2Zllr/Gli3tm1.2Zllr, Pkdcctm1.2Azun/Pkdcctm1.2Azun (more )
Structure Level Pattern Image Note
TS20: radius-ulna pre-cartilage condensation Weak 3C Vlkdelta/delta Gli3delta/delta Expression slightly reduced. compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory