Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:230169
Isaac J, et al., DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo. Cell Death Differ. 2014 Sep;21(9):1365-76
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Assay type:
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Immunohistochemistry
|
MGI Accession ID:
|
MGI:6437525
|
Gene symbol:
|
Alpl
|
Gene name:
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alkaline phosphatase, liver/bone/kidney
|
|
Results
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Specimen
3Ba:
postnatal week 5
(more )
Specimen
3Ba:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal week 5
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: tibia |
Present |
Regionally restricted |
3B1
,
3B2
,
3Ba
|
Expression is in osteoblasts.
|
TS28: long bone metaphysis |
Present |
Regionally restricted |
3Ba
,
3B1
|
Expression is in osteoblasts.
|
TS28: long bone diaphysis |
Present |
Regionally restricted |
3Ba
,
3B2
|
Expression is in osteoblasts.
|
Specimen
3Bb:
(close )
Genetic Background:
|
involves: FVB/NJ
|
Mutant Allele(s):
|
Dlx3tm3Mso/Dlx3tm3Mso Tg(BGLAP-cre)1Clem/0
|
Age:
|
postnatal week 5
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
Conditional mutant.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: tibia |
Present |
Regionally restricted |
3Bb
,
3B3
,
3B4
|
Expression is in osteoblasts that are increased in this mutant.
|
TS28: long bone metaphysis |
Present |
Regionally restricted |
3Bb
,
3B3
|
Expression is in osteoblasts that are increased in this mutant.
|
TS28: long bone diaphysis |
Present |
Regionally restricted |
3Bb
,
3B4
|
Expression is in osteoblasts that are increased in this mutant.
|
|