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Gene Expression Data
Assay Details
Assay
Reference: J:97372 Henion TR, et al., Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons. J Neurosci. 2005 Feb 23;25(8):1894-903
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6437508
Gene symbol: Or8a1b
Gene name: olfactory receptor family 8 subfamily A member 1B
Reporter: GFP
Direct Detection
Results
Specimen 6a beta-3GnT1+/-: postnatal day 10; B3gnt2Gt(KST308)Byg/B3gnt2+, Or8a1btm2Mom/Or8a1b+ (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 6a beta-3GnT1+/-
Specimen 6a beta-3GnT1-/-: postnatal day 10; B3gnt2Gt(KST308)Byg/B3gnt2Gt(KST308)Byg, Or8a1btm2Mom/Or8a1b+ (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 6a beta-3GnT1-/- There was a reduction of labeled neurons in the mutant.
Specimen 6b beta-3GnT1+/-: postnatal day 10; B3gnt2Gt(KST308)Byg/B3gnt2+, Or8a1btm2Mom/Or8a1b+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb olfactory nerve layer Present 6b beta-3GnT1+/-
TS28: main olfactory bulb glomerular layer Present Regionally restricted 6b beta-3GnT1+/- Labeled axons converge on a glomerulus on the dorsomedial surface of the extreme caudal olfactory bulb.
Specimen 6b beta-3GnT1-/-: postnatal day 10; B3gnt2Gt(KST308)Byg/B3gnt2Gt(KST308)Byg, Or8a1btm2Mom/Or8a1b+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb olfactory nerve layer Present 6b beta-3GnT1-/- Labeled axons in the mutant primarily remain in the nerve layer and fail to converge on the typical glomerular position.
TS28: main olfactory bulb glomerular layer Absent 6b beta-3GnT1-/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory