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Gene Expression Data
Assay Details
Assay
Reference: J:287264 Hael CE, et al., The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight. Mol Metab. 2020 Apr;34:43-53
Assay type: RT-PCR
MGI Accession ID: MGI:6437085
Gene symbol: Pomc
Gene name: pro-opiomelanocortin-alpha
Probe: Pomc-pC, Pomc-pD
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR was used to obtain these results.
Results
Image: 7A ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Control P w 16 TS28: hypothalamus Present Not Specified; total RNA involves: C57BL/6 Prdm12tm2c(EUCOMM)Hmgu/Prdm12tm2c(EUCOMM)HmguMale
KO P w 16 TS28: hypothalamus Present (a) Not Specified; total RNA involves: C57BL/6 Prdm12tm2c(EUCOMM)Hmgu/Prdm12tm2c(EUCOMM)Hmgu, Tg(Pomc1-cre)1Gsb/0Male Conditional mutant.
Control P w 16 TS28: hypothalamus Present Not Specified; total RNA involves: C57BL/6 Prdm12tm2c(EUCOMM)Hmgu/Prdm12tm2c(EUCOMM)HmguFemale
KO P w 16 TS28: hypothalamus Present (b) Not Specified; total RNA involves: C57BL/6 Prdm12tm2c(EUCOMM)Hmgu/Prdm12tm2c(EUCOMM)Hmgu, Tg(Pomc1-cre)1Gsb/0Female Conditional mutant.
Notes:
(a) Expression levels are 30% of those found in wild type males.
(b) Expression levels are approximately a third of those seen in wild type females.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory