Smo Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:287091 Gigante ED, et al., ARL13B regulates Sonic hedgehog signaling from outside primary cilia. Elife. 2020 Mar 4;9:e50434
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6437071
Gene symbol:	Smo
Gene name:	smoothened, frizzled class receptor

Antibody:	anti-Smo
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

5A +/+ ©

Specimen 5A +/+: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present	Regionally restricted	5A +/+	Expression is seen in the cilia.
TS17: neural tube lateral wall	Present	Regionally restricted	5A +/+	Expression is seen in the cilia.

5A V358A/+ ©

Specimen 5A V358A/+: embryonic day 10.5; Arl13b^em1Tc/Arl13b⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present	Regionally restricted	5A V358A/+	Expression is seen in the cilia.
TS17: neural tube lateral wall	Present	Regionally restricted	5A V358A/+	Expression is seen in the cilia.

Specimen 5A V358A/V358A: embryonic day 10.5; Arl13b^em1Tc/Arl13b^em1Tc (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present	Regionally restricted	5A V358A/V358A	Expression is seen in the cilia. It is comparable to what is seen in wild type.
TS17: neural tube lateral wall	Present	Regionally restricted	5A V358A/V358A	Expression is seen in the cilia. It is comparable to what is seen in wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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